WIAS Preprint No. 1856, (2013)

POAS4SPM --- A toolbox for SPM to denoise diffusion MRI data


  • Tabelow, Karsten
    ORCID: 0000-0003-1274-9951
  • Mohammadi, Siawoosh
  • Weiskopf, Nikolaus
  • Polzehl, Jörg
    ORCID: 0000-0001-7471-2658

2010 Mathematics Subject Classification

  • 62P10 62G05


  • dMRI, Noise reduction, POAS, msPOAS, SPM8




We present an implementation of a recently developed noise reduction algorithm for dMRI data, called multi-shell position orientation adaptive smoothing (msPOAS), as a toolbox for SPM. The method intrinsically adapts to the structures of different size and shape in dMRI and hence avoids blurring typically observed in non-adaptive smoothing. We give examples for the usage of the toolbox and explain the determination of experiment-dependent parameters for an optimal performance of msPOAS.

Appeared in

  • Neuroinformatics, 13 (2015) pp. 19--29.

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